Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction

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چکیده

Abstract The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C the presence InCl3. Replacement sulfoximines with sulfonimidamides (SIA) has delivered corresponding SIA-based tetrazole. Interestingly, SIA also acts as a surrogate amine to furnish aminotetrazole by-product.

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ژورنال

عنوان ژورنال: SynOpen

سال: 2022

ISSN: ['2509-9396']

DOI: https://doi.org/10.1055/a-1981-9151