Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction
نویسندگان
چکیده
Abstract The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C the presence InCl3. Replacement sulfoximines with sulfonimidamides (SIA) has delivered corresponding SIA-based tetrazole. Interestingly, SIA also acts as a surrogate amine to furnish aminotetrazole by-product.
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ژورنال
عنوان ژورنال: SynOpen
سال: 2022
ISSN: ['2509-9396']
DOI: https://doi.org/10.1055/a-1981-9151